| Society to Explore and Record Christian History | Edmonton | $438K |
| Socio-Economic and Environmental Development Solutions (SEEDS) | Toronto | $5,804 |
| Socks 4 Souls Canada Inc. | Etobicoke | $223K |
| Socks for Change | ST Catharines | $43K |
| SoCo Beach Project | Port Dover | $257K |
| Socrates Hellenic School of Mississauga and District | Mississauga | — |
| Sodexo Foundation Inc/fondation Sodexo Inc | Burlington | $386K |
| Soeurs de la Charite de Notre Dame d'Evron | Edmonton | $519K |
| Soeurs de la charité de Saint-Hyacinthe au Québec | Saint-Hyacinthe | — |
| Soeurs de la Charite de Saint-Louis du Québec | Levis | — |
| Soeurs de la Presentation de Marie du Quebec | Saint-Hyacinthe | — |
| Soeurs de la Providence - Émilie Gamelin | Montreal | — |
| Soeurs de la Providence/Sisters of Providence/Hermanas de laProvidencia | Montréal | — |
| Soeurs de l'Agneau | Sainte-Petronille | $79K |
| Soeurs de l'Institut Jeanne d'Arc | Ottawa | — |
| Soeurs de Notre-Dame des Douleurs (montreal) | Montreal | $1.4M |
| Soeurs de Notre-Dame du Sourire | Montreal | $299K |
| Soeurs de Saint-François-D'assise du Canada | Quebec | — |
| Soeurs de Saint-Paul-de-Chartres | Montreal | — |
| Soeurs de Sainte-Anne | Lachine | $48K |
| Soeurs de Sainte-Croix | Saint-Laurent | — |
| Soeurs de Sainte-Croix | Saint-Laurent | — |
| Soeurs du Sauveur and Or Sisters of the Saviour | Winnipeg | — |
| Soeurs Franciscaines missionnaires de L'Immaculée-Conception | Saint-Laurent | — |
| Soeurs Missionnaires de Notre-Dame des Anges | Sherbrooke | — |
| Soeurs missionnaires de Notre-Dame des Apôtres (Montréal) | Montreal | $966K |
| Soeurs Missionnaires du Saint-Esprit-District du Canada | Montreal | $902K |
| Soeurs Notre-Dame de la Visitation de Sainte Marie | Rouyn-Noranda | $313K |
| Sofia House Inc | Regina | $1M |
| Sofina Foundation | Markham | $770K |
| Soft Bones Canada | Lethbridge | $2,600 |
| Sogn Family Foundation Incorporated | Shaunavon | $156K |
| Soh Lim Poh Paul Foundation | Vancouver | $17K |
| Sohian Overseas Education Society | Delta | — |
| Sohrae Church | Toronto | $162K |
| Sohrae Youth Orchestra | Toronto | $29K |
| Soil and Water Conservation Society Ontario | Guelph | $1,082 |
| Soil Conservation Council of Canada | Warman | $92K |
| Soins Chabad / Chabad Care | Montreal | $410K |
| Soins Palliactifs The Three Paths - Palliactive Care | Montreal | $351K |
| Soins Palliatifs Horizon-Timmins Inc./horizon-Timmins Palliative CARE Inc. | Timmins | $125K |
| Soins pédiatriques mobiles Montréal SP2M | Montreal | $130K |
| Sointula Community Church | Sointula | $104K |
| Sojourn Church | Paris | $427K |
| Sojourners Camp & Wilderness Society | Calgary | $5,990 |
| Sojust Holdings | Calgary | — |
| Soka Gakkai International Association of Canada Association de la Soka Gakkai Internationale du Canada | Toronto | $3.9M |
| Solace Grief Support Society | High River | $102K |
| Solace House Canada | Quesnel | — |
| Solar Schools Canada Les Ecoles Solaires du Canada | Halifax | — |
| Solar Stage | Toronto | — |
| Solari Foundation | Vancouver | $200 |
| Solaris Autism Services Inc. | Picton | — |
| Solaris Centre | Saint-Laurent | $22K |
| Solbrekken Evangelistic Association of Canada | Edmonton | $94K |
| Solcz Family Foundation | Windsor | $5.4M |
| Soldiers' Memorial Health Auxiliary Society | Middleton | $19K |
| Soldiers Memorial Hospital Foundation | Middleton | $886K |
| Sole Responsibility | Ottawa | $5,013 |
| Soleil des Nations | ST-Laurent | — |
| Soleil des orphelins | Laval | $1.3M |
| Solel Congregation of Mississauga | Mississauga | $622K |
| Soli-Can Lac Saint-Jean Est (solidarite-Cancer) | Alma | $1.4M |
| Solid Families Foundation | Brampton | $0 |
| Solid Foundation Canada | Niagara Falls | — |
| Solid Futures Learning Centre Co-operative Limited | Regina | $748K |
| Solid Ground Bible Study Ministries | Cambridge | $286K |
| Solid Rock Baptist Chapel of Mississauga | Milton | $47K |
| Solid Rock Baptist Church of Alberta | Rocky View County | $947K |
| Solid Rock Biker Church | Delta | $15K |
| Solid Rock Christian Assembly | Etobicoke | $502K |
| Solid Rock Christian Fellowship World Outreach Society | Abbotsford | $2.2M |
| Solid Rock Community Church Inc. | Swan River | $326K |
| Solid Rock Community Church of the Nazarene | Toronto | — |
| Solid Rock Equipping Ministries Inc. | Shelburne | $100 |
| Solid Rock Free Lutheran Church of Camrose | Camrose | $332K |
| Solid Rock Miracle Centre | Scarborough | $59K |
| Solid Rock Wesleyan Church | Mount Pearl | $150K |
| Solid Rock Youth and Family Foundation | Taber | — |
| Solidarite Beauce-Sartigan Inc. | ST-Georges | $4,880 |
| Solidarité Bresil-Outaouais (sbo) | Gatineau | $11K |
| Solidarité citoyenne Portneuf | Saint-Basile | $1M |
| Solidarité de parents de personnes handicapées inc. | Montreal | $913K |
| Solidarite Deuil d'Enfant de Quebec | Ste-Foy | $3,815 |
| Solidarité Enfants d'ici et d'ailleurs | Quebec | $100K |
| Solidarité Ethnique Régionale de la Yamaska | Granby | $1.7M |
| Solidarité Familles | Quebec | $1.4M |
| Solidarite Jeunesse | Ottawa | $354K |
| Solidarite Justice et Foi Petite Nation | Saint-Sixte | — |
| Solidarité Laurentides - Amérique Centrale (SLAM) | Saint-Jerome | $136K |
| Solidarite Mercier-Est | Montréal | $783K |
| Solidarité Montérégie Amérique Centrale (SMAC) | Richelieu | $142K |
| Solidarite Nord-Sud des Bois-Francs Inc. | Victoriaville | $189K |
| Solidarite Regionale d'Aide et d'Accompagnement pour la Defense des Droits en Sante Mentale du Centre du Quebec/ Mauricie. | Trois-Rivieres | $296K |
| Solidarité Sainte-Ursule | Quebec | $3.5M |
| Solidarité sociale de Rawdon | Rawdon | $242K |
| Solidarité Sud (sol-Sud) | Québec | $61K |
| Solidarity in Action Incorporated | Burlington | — |
| Solidarqc | Île Bizard | — |
| Solidifi Charitable Foundation | Thornhill | $32K |
| Solitude Myriam Inc. | Mirabel | $139K |
| Solitude St-Joseph Inc. | Victoriaville | — |
| Solitudes Wildlife Rehabilitation Centre (ontario) | Kearney | $3,387 |
| Sollicité | Montreal | $380K |
| Solman Family Foundation Inc. | Winnipeg | — |
| Solo Chicken Productions Incorporated | Fredericton | $214K |
| Solo Deo Monastery | Duncan | $118K |
| Solo Swims of Ontario Inc. | Stoney Creek | $17K |
| Soloman Brother's Christian Ministry | North York | $55K |
| Solomon Ministry | North York | $59K |
| Solomon Schechter Academy | Montreal | $9.2M |
| Solor Lutheran Church | Chinook | $3,043 |
| Solun Theatre Society | Montreal | $163 |
| Solution Embassy of Christ Ministries Inc. | Brampton | — |
| Somali Canadian Cultural Society of Edmonton | Edmonton | $191K |
| Somali Canadian Education and Rural Development Organization(scerdo) | Edmonton | — |
| Somali Canadian Society of Calgary | Calgary | $529K |
| Somali Centre for Family Service | Ottawa | $2.8M |
| Somali Christian Ministries | Etobicoke | — |
| Somali Communities Foundation | Toronto | $111K |
| Somali Community in Hamilton | Hamilton | $213K |
| Somali Hope Academy Foundation | Ottawa | $249K |
| Somali Islamic Society of BC | Surrey | $458K |
| Somali Islamic Society of Canada | Etobicoke | $1.2M |
| Somali Relief Network of North America | North York | $389K |
| Somang Christian Reformed Church | Edmonton | $132K |
| Somang Mission Community | Merritt | $47K |
| Somar Family Foundation | Calgary | $20K |
| Sombra Township Child CARE | Port Lambton | $1.7M |
| Sombra Township Museum | Sombra | $37K |
| Sombrilla International Development Society | Edmonton | $203K |
| Some Assembly Arts Society | Vancouver | $173K |
| Some Other Solutions Society for Crisis Prevention | Fort McMurray | $935K |
| Some Place Special Christian Day CARE and Academy | Markham | $6.7M |
| Some Strange Reason Theatreworks Inc. | Toronto | — |
| Somenos Marsh Wildlife Society | Duncan | $289K |
| Somers Family Foundation | Westmount | $4.6M |
| Somerset Academy | Markham | $1.6M |
| Somerset and Area Elderly and Infirm Persons Housing CO Incorporated | Somerset | $360K |
| Somerset Bible Chapel | Somerset | — |
| Somerset Foundation | Vancouver | $928K |
| Somerset Home and School Association | Berwick | $33K |
| Somerset Lorne Citizen Museum | Somerset | $10K |
| Somerset Pre-School Inc. | Saint John | $944K |
| Somerset Rendez-Vous Centre Inc. | Somerset | $21K |
| Somerset Villa Inc. | Somerset | $139K |
| Somerset West Community Health Centre | Ottawa | $20.9M |
| Something Special Children's Centre | Kingston | $1.4M |
| Sommerfeld Charitable Trust | Portage la Prairie | $141K |
| Sommerfeld Mennonite Church Of Manitoba | Winkler | $2M |
| Son Light Missions Canada | Milverton | — |
| Sonbow Ministries | Dacre | $16K |
| Songs of Deliverance Ministries Association of Alberta | Edmonton | — |
| Songwriters Association of Canada | Toronto | $362K |
| Sonia's School of Ukrainian Dance Inc. | Warman | $81K |
| Sonlife Community Church | Dartmouth | $125K |
| Sonlight Christian Reformed Church Inc. | Regina | $143K |
| Sonlight Ministries | Calgary | $71K |
| Sonningdale Pentecostal Church | Sonningdale | $59K |
| Sonora Baptist Church | Sherbrook | $7,107 |
| Sonora Evangelical Ministries | Whitehorse | — |
| Sonrisa Foundation | London | $1M |
| Sonrise Christian Academy | Belleville | — |
| Sonrise Christian Centre | Whitehorse | $36K |
| Sonrise Christian Fellowship | Penticton | $2,000 |
| Sonrise Christian Reformed Church | Ponoka | $464K |
| Sonrise Community Baptist Church | Calgary | $80K |
| Sonrise Foundation | Kelowna | $3M |
| Sonrise Full Gospel Church | Surrey | $913K |
| Sonrise Ministries Inc. | Corner Brook | $311K |
| Sonrise New Directions Society | Prince George | $192K |
| SonRise Pentecostal Camp Lac Ste Anne | Yellowhead County | $111K |
| Sons of Italy (hamilton) Charitable Corporation | Hamilton | $5M |
| Sons of Jacob Synagogue of Belleville | Belleville | $31K |
| Sons of Mary Mother of Mercy Congregation | Garson | $568K |
| Sons of Norway Foundation in Canada | Calgary | $181K |
| Sons of Salvation Christian Ministries of Canada | Wellesley | $90K |
| Sons of Scotland Foundation | Ottawa | $700 |
| Sonset Solutions Canada | Cambridge | $260K |
| Sonshine Christian Ministries Inc. | Regina | $17K |
| Sonshine Community Ministries (Ottawa) | Orleans | $1.6M |
| Sonship International Ministries Canada | Calgary | $31K |
| Sonus Voices | Grimsby | $7 |
| Sony Canada Charitable Foundation | North York | $249K |
| Soo Arena Association | Sault Ste. Marie | $745K |
| Soofi Association of North America | Hamilton | $2,019 |
| Soojung Presbyterian Church | Langley | -$76K |
| Sooke And Juan De Fuca Health Foundation | Sooke | $7,860 |
| Sooke Autism Support Society | Sooke | — |
| Sooke Baptist Church | Sooke | $264K |
| Sooke Congregation of Jehovah's Witnesses Sooke British Columbia | Sooke | $74K |
| Sooke Elderly Citizens' Housing Society | Sooke | $5.6M |
| Sooke Family Resource Society | Sooke | $4.8M |
| Sooke Fine Arts Society | Sooke | $691K |
| Sooke Folk Music Society | Sooke | — |
| Sooke Food Bank Society | Sooke | $561K |
| Sooke Harbour Players Society | Sooke | $73K |
| Sooke Hospice Society | Sooke | $24K |
| Sooke Meals On Wheels Association | Sooke | $90K |
| Sooke Options for Community Living Association | Sooke | $744K |