| The Saskatoon Concert Band | Saskatoon | $119K |
| The Saskatoon Gallery and Conservatory Corporation | Saskatoon | — |
| The Saskatoon Lake Agricultural Society | Wembley | $257K |
| The Saskatoon Lighthouse Foundation Corp. | Airdrie | $2,091 |
| The Saskatoon Native Ministry Inc. | Saskatoon | — |
| The Saskatoon Philippine Senior Citizens Foundation Inc. | Saskatoon | $17K |
| The Saskatoon Regional Science Fair Inc. | Saskatoon | $12K |
| The Satellite Video Exchange Society | Vancouver | $528K |
| The Satir Institute of the Pacific | Langley | $180K |
| The Saturna Island Volunteer Fire Department Association | Saturna Island | $13K |
| The Saugeen Railtrail Association | Port Elgin | $35K |
| The Saul and Claribel Simkin Centre Foundation Inc. | Winnipeg | $1.6M |
| The Saul and Claribel Simkin Centre Personal Care Home Inc. | Winnipeg | $22.7M |
| The Sault College of Applied Arts and Technology | Sault Ste. Marie | $137.7M |
| The Sault Ste Marie Community Theatre Centre | Sault Ste Marie | $357K |
| The Savary Island Christian Fellowship | Powell River | $6,411 |
| The Savary Island Land Trust Society | Lund | $91K |
| The Saville Salas Foundation | Toronto | $14K |
| The Saviour Baptist Church | Etobicoke | $121K |
| The Savoy Foundation Inc./La fondation Savoy Inc. | Saint-Jean-Sur-Richelieu | $593K |
| The Savoy Theatre Society | Glace Bay | $1.4M |
| The Savvas Chamberlain Family Foundation | Waterloo | $5.9M |
| The Sawatzky Specialties Foundation | Stony Plain | $683K |
| The Scarborough Concert Band | Scarborough | $3,757 |
| The Schad Foundation | Woodbridge | $11.5M |
| The Schmeelk Canada foundation LA FONDATION SCHMEELK DU CANADA | Montreal | — |
| The Schmerz Family Foundation | North York | $542K |
| The Schneider Family Foundation | Etobicoke | $2M |
| The Schneider Male Chorus | Waterloo | $27K |
| The Scholarship Fund of the Canadian Federation of University Women Oshawa and District | Whitby | — |
| The School of Contemporary Dancers Inc. | Winnipeg | $924K |
| The School of Dance (ottawa) Pre-Professional Programme Inc. | Ottawa | $1.5M |
| The School of Restoration Arts at Willowbank | Queenston | $536K |
| The School of the Evangelists | Ajax | $90K |
| The Schroeder Foundation | Toronto | $99.1M |
| The Schubert Foundation | Vernon | $194 |
| The Schulich Foundation | Toronto | $78M |
| The Schumacher Family Foundation | Toronto | $1,673 |
| The Schuster And Osten Family Foundation | Montreal | $13K |
| The Schwenger Family Foundation | Burlington | $562K |
| The Science East Association Inc. | Fredericton | $1.6M |
| The Scoliosis Association of British Columbia Chapter 100 | Saanichton | $0 |
| The S'Cool Public Education Foundation | Toronto | $52K |
| The Scotia Creek Foundation | Whistler | — |
| The ScotiaMcLeod Charitable Foundation | Toronto | $2.7M |
| The Scotlyn Foundation | Calgary | $92K |
| The Scott Griffin Foundation | Toronto | $412K |
| The Scott Island Foundation | Ottawa | — |
| The Scott Nelson Family Foundation | ST. Albert | — |
| The Scott Reid Foundation / Scholarship Fund | Brighton | $19K |
| The Scott Young Foundation | Burlington | $500 |
| The Scottish Borderers Foundation | Belle River | $177K |
| The Scottish Rite Charitable Foundation Learning Centre for Calgary | Calgary | $129K |
| The Scottish Rite Charitable Foundation Learning Centre for Edmonton | Edmonton | $85K |
| The Scottish Rite Charitable Foundation Learning Centre For Halifax Inc. | Dartmouth | $355K |
| The Scottish Rite Charitable Foundation Learning Centre for Hamilton | Hamilton | $1M |
| The Scottish Rite Charitable Foundation Learning Centre for London | London | $50K |
| The Scottish Rite Charitable Foundation Learning Centre for Moncton Inc. | Riverview | $38K |
| The Scottish Rite Charitable Foundation Learning Centre for Windsor Inc. | Windsor | $188K |
| The Scottish Rite Charitable Foundation Learning Centre - Valley of Barrie | Barrie | $139K |
| The Scottish Rite Charitable Foundation Learning Centres for B.C. | Vancouver | $148K |
| The Scottish Rite Charitable Foundation of Canada | Hamilton | $2M |
| The Scottish Rite Club of Victoria District Endowment Fund | Fenelon Falls | $2,715 |
| The Scottish Studies Foundation Inc. | Ajax | $15K |
| The Scowen Foundation | London | $12K |
| The Scrimgeour Family Charitable Foundation Trust | London | $2.1M |
| The SCTV Monument Society | Edmonton | $1,324 |
| The Sea Hawks Toronto (youth Sailing Club) | Glen Williams | $27K |
| The Seaforth Highlander Cadets of Canada | Vancouver | — |
| The Seaforth Highlanders of Canada Foundation | Vancouver | $188K |
| The Seagull Foundation | Pugwash | $91K |
| The Search Party Theatre Company Society | Vancouver | $145K |
| The Seaside Cemetery Club | Clarks Harbour | $6,986 |
| The Seaside Cemetery Committee | Kingsburg | $150 |
| The Seasted Foundation | Victoria | $639K |
| The Seaway Christian Church | Prescott | $121K |
| The Seaway Winds | Cornwall | $12K |
| The Sebastopol Heritage and Historic Society | Eganville | — |
| The Second Adams Charitable Foundation Inc. | Regina | $34K |
| The Second Mile Club of Toronto | Toronto | $1.1M |
| The Second Story Art Society | Calgary | $307K |
| The Secret Handshake Schizophrenia Peer Support Group / Network | Toronto | $38K |
| The Secrets of Radar Museum | London | $75K |
| The Sedgewick and District Agricultural Society | Sedgewick | $180K |
| The Seed Foundation | Toronto | — |
| The Seedhouse Family Foundation | Barrie | $85K |
| The Seeing Eye Organization | Toronto | $694K |
| The Segelberg Trust | Halifax | $104K |
| The Sela Family Foundation/La fondation familiale Sela | Mount-Royal | — |
| The Self-Help Connection Clearinghouse Association | Halifax | $221K |
| The Selfie Foundation | Millbrook | $0 |
| The Sellwoods | Bowmanville | — |
| The Seltzer-Chan Pond Inlet Foundation | Toronto | $45K |
| The Selwyn Public Library Board | Bridgenorth | $932K |
| The Semiahmoo Foundation | Surrey | $892K |
| The Seminary of The Christian Community in North America | Vaughan | $383K |
| The Senior Citizens Choir of Winnipeg | Winnipeg | $5,439 |
| The Senior Citizens' Club of Fenelon Falls Ontario | Fenelon Falls | $160K |
| The Seniors' Research Group of Chinese Opera and Music | Vancouver | — |
| The Senlac Community Memorial Hall CO | Senlac | $17K |
| The Seokwang Presbyterian Church of Montréal | Cote Saint-Luc | $48K |
| The Serbian Cultural Society 'kolo' Inc. | Winnipeg | — |
| The Serbian Eastern Orthodox Church of ST. Archangel Michael | Toronto | $154K |
| The Serbian Heritage Academy of Canada | Toronto | $33K |
| The Serbian Orthodox Centre 'holy Trinity' | Hamilton | $135K |
| The Serbian Orthodox Church-School Congregation Holy Trinity | Westmount | $532K |
| The Serbian Orthodox Diocese of Canada | Campbellville | $2.3M |
| The Serenity Free Will Baptist Church and Ministries of Fredericton New Brunswick Canada | Fredericton | $743K |
| The Sergeant Tommy Prince MM SS Memorial Corporation | Selkirk | $2,587 |
| The Serpentine Enhancement Society | Surrey | $31K |
| The Serruya Family Foundation | Markham | $1.3M |
| The Sertoma Foundation of Canada | Chatham | $20K |
| The Service Battalion Senate Incorporated | Winnipeg | $12K |
| The SET Fund | North York | $409K |
| The Seton Centre Inc. | Carberry | $14K |
| The Seton Valley Volunteer Firefighters Society | Seton Portage | — |
| The Seven Churches and Charitable Works Foundation | Cowansville | $138K |
| The Seven Oaks School Division | Winnipeg | $186.6M |
| The Seventh Step Society of Canada | Calgary | $862K |
| The Sexsmith and District Museum Society | Sexsmith | $235K |
| The Sexsmith & District Agricultural Society | Sexsmith | $594K |
| The Seymour Salmonid Society | Vancouver | $538K |
| The Shaama Centre for Seniors and Women | Edmonton | $379K |
| The Shabinsky Family Foundation | Ottawa | $449K |
| The Shakespeare Company Theatre in the Round Guild | Calgary | $308K |
| The Shakespeare Globe Centre of Canada | Toronto | $503 |
| The Shalem Foundation Canada | Toronto | $1M |
| The Shamrock Children's Christmas Society | Calgary | — |
| The Shanahan Carriage Foundation | Keswick | $248K |
| The Shane Daye and Keith Nash Memorial Foundation | Sherwood Park | $20K |
| The Shania Twain Foundation | Toronto | $95K |
| The Shannex Cares Foundation | Halifax | — |
| The Shannon Day CARE Society | Vancouver | $596K |
| The Shannon Family Foundation | Rothesay | — |
| The Share Foundation Corporation | Burlington | — |
| The Share Shop | Hinton | $213K |
| The Shared Path Consultation Initiative | Toronto | $71K |
| The Sharing Farm Society | Richmond | $455K |
| The Sharing Foundation | North York | $1.9M |
| The Sharing Place of Toronto Inc. | Toronto | $148K |
| The Sharing Place Orillia Incorporated | Orillia | $4.8M |
| The Sharing Well Foundation | Chemainus | $9,500 |
| The Sharon Azrieli Foundation For The Arts La Fondation Sharon Azrieli Pour Les Arts | Westmount | $5.4M |
| The Sharon Temple Museum Society | Sharon | $1.5M |
| The Sharp Foundation | Toronto | $3.4M |
| The Sharpe Indigenous Charitable Foundation | Toronto | — |
| The Shaun Anthony Lewis Cable Foundation | Edmonton | $25K |
| The Shaw House Corporation | Toronto | $114K |
| The Shawana Foundation | Calgary | $714K |
| The Shayam Kaushal Charitable Foundation | Toronto | — |
| The Shearwater Aviation Museum Foundation | Halifax | $129K |
| The Shechinah Glory International Ministries | North York | — |
| The Sheila & Con Di Nino Foundation | Toronto | $4,299 |
| The Sheldon Inwentash and Lynn Factor Charitable Foundation | Calgary | $40K |
| The Shellbrook Senior Citizens CO-Operative Club | Shellbrook | $36K |
| The Shelley Gautier Para-Sport Foundation | Toronto | — |
| The Shello Charitable Foundation | Thornhill | — |
| The Shelter Reformed Church of Edmonton | Sherwood Park | $900 |
| The Shen Family Charitable Foundation | Toronto | $1.9M |
| The Shenker Family Foundation | Toronto | — |
| The Sheonoroil Foundation | Halifax | $6,492 |
| The Shepherd's Centre (brockville) Foundation | Brockville | $9,359 |
| The Shepherd's Christian Center for Spiritual Renewal Inc. | Swift Current | $1,402 |
| The Shepherd's Lunch Room | New Glasgow | $11K |
| The Shepherds' Trust | Toronto | $16.1M |
| The Shepody Cemetery Trust | Hopewell Cape | $0 |
| The Sheppard Memorial Foundation | Oliver | — |
| The Sheptytsky Council No 5079 Charitable Trust | Etobicoke | $3,865 |
| The Sheridan College Institute of Technology and Advanced Learning | Oakville | $519.8M |
| The Sherry Taylor Drew Foundation | Toronto | $99K |
| The Sherwood Cemetery Company | Charlottetown | $112K |
| The Sheryl and Ronald Black Family Foundation | Montreal | — |
| The Shewan Foundation | Langley | $339K |
| The Shia Muslim Community of British Columbia | Richmond | $1.7M |
| The Shidaa Foundation | Woodbridge | $8,334 |
| The Shields and Woodrow Foundation | Toronto | $139K |
| The Shields Foundation | Richmond | $616K |
| The Shiloah Pentecostal Church | Toronto | — |
| The Shindleman Foundation Inc. | Winnipeg | $755 |
| The Shining Lighte (Leaders in Generational Healing Through Empowerment and Education) Youth Charity | Brampton | $79K |
| The Shining Star Foundation | Richmond Hill | $1.7M |
| The Ship's Company Society | Parrsboro | $535K |
| The Shirdi Sai Mandir and Cultural Centre | Scarborough | $2.2M |
| The Shirley and William B Miller Family Foundation | Montreal | $26K |
| The Shoal Lake Donor's Choice | Shoal Lake | $15K |
| The Shoe Project | Toronto | — |
| The Shoebox Project for Shelters | Toronto | $845K |
| The Shoebox Workshop Waterloo Region | Kitchener | $49K |
| The Shohet Foundation | Toronto | — |
| The Shore Church | North Vancouver | $326K |
| The Shrage Zimmerman Memorial Fund | Montreal | $500K |
| The Shrine of Santo Nino de Cebu | Agassiz | $50K |
| The Shtiebel | Toronto | $1.7M |
| The Shuswap Outdoor Learning Foundation | Canoe | $2 |
| The Sicamous-Malakwa Adult Resource Training and Community Living Society | Sicamous | $3,931 |
| The Sickle Cell Foundation of Alberta | Edmonton | — |
| The Sickle Circle of Manitoba Inc. | Winnipeg | $32K |
| The Sid and Denise Levin Charitable Foundation | Toronto | $114K |
| The Sidekick Players Club | Delta | $15K |
| The Sidney Crosby Foundation | Halifax | $148K |