| International Translators and Interpreters Foundation | Calgary | — |
| International United Bethel Assembly of Ontario | North York | — |
| International Vegan Film Festival | Ottawa | — |
| International Vision Organization | Calgary | $8,493 |
| International Vision Volunteers Canada | Courtenay | $27K |
| International Wellness and Environment Foundation | Vancouver | — |
| International Widows & Orphans Fund Society | Nanaimo | $165K |
| International Women of Saskatoon IWS Inc. | Saskatoon | $4.9M |
| International Worship Centre Inc. | Winnipeg | $2M |
| International Youth Evangelization and Training Missions | Paris | $17K |
| International Youth Fellowship | Toronto | $103K |
| Internet for Humanity Society | North Saanich | $340K |
| Internet Sense First / Premier Sens Internet | London | $14K |
| InterPilot Aviation Safety Foundation | Montreal | $148K |
| Interprovincial School Development Association | Halifax | $609K |
| Intersection Music & Arts | Toronto | $5,937 |
| Intersections Media Opportunities for Youth Society | Richmond | $1.2M |
| INTERTRIBAL CHRISTIAN COMMUNICATIONS (CANADA) Inc. | Langdon | $238K |
| Interval House | Etobicoke | $5.2M |
| Interval House of Hamilton-Wentworth | Hamilton | $3.2M |
| Interval House of Ottawa-Maison Interval d'Ottawa | Ottawa | $2.4M |
| Intervalle | Thetford Mines | $618K |
| Interwoven Connections Connexions Entrelacées | Ottawa | $1.7M |
| Into All the World Inc. | Guelph | $1.2M |
| Into the Woods Early Learning Childcare Society | Qualicum Beach | $697K |
| Intola Baptist Church | Thunder Bay | $277K |
| Intracorp Canadian Foundation | Vancouver | $48K |
| Intrada Brass | Oakville | $95K |
| Intred Training and Education | Toronto | — |
| Intrepid Theatre Company Society | Victoria | $1M |
| Intriciti Ministries Incorporated | Toronto | $280K |
| Inuit Art Foundation | Toronto | $2.9M |
| Inuit Association of Manitoba (I AM...) Inc. | Winnipeg | $6.6M |
| Inuit Broadcasting Corporation | Ottawa | $2.6M |
| Inuit Tapiriit Kanatami | Ottawa | $26.9M |
| Inuk First Aid Instruction & Health Promotion | Guelph | $6,351 |
| Inuuqatigiit Centre For Inuit Children Youth And Families | Ottawa | $10.8M |
| Inuvialuit Charitable Foundation | Inuvik | $377K |
| Inuvialuit Education Foundation | Inuvik | $527K |
| Inuvik District Education Authority | Inuvik | — |
| Inuvik Food Bank | Inuvik | $131K |
| Inuvik Homeless Shelter Advisory | Inuvik | $248K |
| Inuvik Transition House Society | Inuvik | $678K |
| Inuvik Youth Centre Society | Inuvik | $180K |
| Invasive Species Council of British Columbia Society | Williams Lake | $3.4M |
| Invasive Species Council of Metro Vancouver Society | Vancouver | $106K |
| Inventor Academy | Richmond Hill | $120K |
| Inverary Congregation of Jehovah's Witnesses Inverary Ontario | Inverary | $52K |
| Inverary Manor Auxiliary | Inverness | $5,730 |
| Inverary United Church | Inverary | $123K |
| Inverhuron & District Ratepayers Association Charitable Trust | London | — |
| Invermere Companion Animal Network Society | Invermere | $64K |
| Invermere Congregation of Jehovah's Witnesses Invermere British Columbia | Radium Hot Springs | $45K |
| Invermere Film Festival | Toronto | $55K |
| Invermere Health CARE Auxiliary Society | Invermere | $726K |
| Inverness Community Church | Inverness | $258K |
| Inverness Consolidated Memorial Hospital Auxiliary | Inverness | $92K |
| Inverness Consolidated Memorial Hospital Charitable Foundation | Inverness | $247K |
| Inverness County Council of the Arts | Inverness | $211K |
| Inverness Food Bank Society | Inverness | $40K |
| Inverness Pastoral Charge | Saint-Jean-De-Brebeuf | $3,769 |
| Investing Hope Foundation | Calgary | $338K |
| Investing in Children Inc. | London | — |
| Investing in Christ's Call International | Scarborough | $0 |
| InVision 20/20 | Vancouver | $251K |
| Invitation Ministries Inc. | Moose Jaw | $29K |
| Invitation the Quilt of Belonging | Williamstown | $5,610 |
| Inwood Manor Inc. | Inwood | — |
| Inzira y'Urumuri/Le chemin de la lumière (IU/CL) | Sudbury | $18K |
| Iodine Global Network | Renfrew | $2.2M |
| Iof Foresters Prevention of Child Abuse Fund | Don Mills | — |
| IOM Mannkind Charitable Society | Surrey | $403K |
| Iona Christian Fellowship Church | Iona Station | $61K |
| Iona College | Windsor | — |
| Iona Community Preservation Association | Iona | $2,304 |
| Iona Presbyterian Church | Dartmouth | $105K |
| Iona Station Baptist Church | ST Thomas | — |
| Iona Volunteer Fire Department | Iona | $121K |
| Iona (Willowdale) Presbyterian Church | North York | — |
| Ioof. Seniors Homes Inc. | Barrie | $35.1M |
| IPAF International Public Art Festival / IPAF Festival international d'art public | Westmount | — |
| iPartner India Canada | Toronto | $223K |
| Ippnw Canada (international Physicians for the Prevention of Nuclear War) | Ottawa | $111K |
| Ipsita Nova Dance Projects Inc. | Toronto | $297K |
| Iqaluit Christian Fellowship | Iqaluit | $194K |
| Iqaluit congregation of Jehovah's Witnesses Iqaluit Nunavut | Iqaluit | $49K |
| Iqaluit District Education Authority | Iqaluit | — |
| Iqaluit Humane Society 2007 | Iqaluit | $558K |
| Iqaluit Pentecostal Church | Iqaluit | $258K |
| Iqbal Dossani Family Foundation | Saint-Laurent | $259K |
| IQRA Education Society | Surrey | $6M |
| IQRA Foundation | Montreal | $618K |
| Iqra Islamic School | Mississauga | $837K |
| Iranian Church of Richmond Hill | Richmond Hill | $94K |
| Iranian Women's Organization of Ontario | North York | $172K |
| Iraq Hope Foundation | Milton | — |
| Iraqi Community Services of Ontario | Etobicoke | — |
| Ireland Outreach (canada) Inc. | Whitby | $38K |
| Irene Cooper Educational Trust | Victoria | $37K |
| Irene E. Nordwich Foundation Inc. | Winnipeg | $147K |
| Iris Kirby House | ST. John's | $4M |
| Iris Ministries Canada | Aurora | $1.2M |
| Iris Noir | Mont-Joli | — |
| Iris Residential Inns and Services | Windsor | $1.7M |
| Iris the Dragon | Perth | $409K |
| Irish Choral Society of Canada | Toronto | — |
| Irish Heritage Quebec/héritage Irlandais Québec | Quebec | $7,395 |
| Irish Regiment (sudbury) Association | Sudbury | $2,905 |
| Irishtown Community Centre Inc. | Irishtown | $163K |
| Irma Alliance Church | Irma | $190K |
| Irma and District Historical Society | Irma | $19K |
| Irma and Vincenzo Pulla Charitable Foundation | Toronto | $122K |
| Irma Fire Fighters Association | Irma | $24K |
| Irma J. Brydson Foundation | Victoria | $935K |
| Irma United Church Official Board | Irma | — |
| Iron Bridge United Church | Thessalon | — |
| Iron Creek Museum | Lougheed | $28K |
| Iron Hill Union Cemetery | Cowansville | $2,586 |
| Iron River Open Bible Fellowship | Bonnyville | $25K |
| Iroquois Falls Access Transit/Transport Adapté | Iroquois Falls a | $74K |
| Iroquois Falls Adult Learning Centre | Cochrane | $422K |
| Iroquois Falls Arts Council/Conseil des arts d'Iroquois Falls | Iroquois Falls a | $64K |
| Iroquois Falls Bible Chapel | Iroquois Falls | $17K |
| Iroquois Falls Family Health Team | Iroquois Falls | $1.1M |
| Iroquois Falls Music Festival Committee | Iroquois Falls | $197 |
| Iroquois Falls Pentecostal Church | Iroquois Falls | $84K |
| Iroquois Falls Pre-School Centre Pre-Scolaire Iroquois Falls | Iroquois Falls | $279K |
| Iroquois Falls Public Library Board | Iroquois Falls a | $217K |
| Iroquois United Church Cemetery Board | Iroquois | $82K |
| Irricana Food Bank | Irricana | $11K |
| Irricana United Church | Irricana | $119K |
| Irvin Macklin Charity Foundation | Grande Prairie | $1.2M |
| Irving and Molly Levins Foundation | Toronto | $232K |
| Irving Greenberg Memorial Camp Fund | Ottawa | $32K |
| Irving L. Rosen Foundation | North York | $7,160 |
| Isaac & Evelyn Grubner Charitable Trust | North York | $36K |
| Isaacs Harbour Cemetery Association Beautification Fund | Isaacs Harbour | $7,183 |
| Isabel Adams Coburn Scholarship Trust | Fredericton | — |
| Isabel Simpson Hospital Trust | Halifax | $16K |
| Isabella Community Centre | Isabella | $24K |
| Isaiah 40 Foundation | Montreal | $101K |
| Isaiah 61 Foundation | Victoria | $112K |
| Isaiah House Special CARE Society | Halifax | $753K |
| Isaiah Projects | Guelph | $253K |
| Isaksimagit Inuusirmi Katujjiqatigiit Embrace Life Council | Iqaluit | $2.8M |
| ISANS. Immigrant Services Association of Nova Scotia | Halifax | $42.3M |
| ISARUIT Inuit Women's Sewing Centre in Ottawa | Ottawa | $902K |
| Isberg Charitable Trust | Toronto | $139K |
| Isee Solutions Society | Kelowna | — |
| Isgonish Marsh Burying Grounds Association | Debert | $605 |
| Isha Foundation | Burlington | $767K |
| Ishan Forever Young Foundation | Mississauga | — |
| Ishtar Women's Resource Society | Langley | $3.6M |
| Isisa Foundation | Vancouver | $7,200 |
| Isisters Technology Mentoring Inc. | Ottawa | $278K |
| Islam CARE Centre | Ottawa | $194K |
| Islamic Academy of Canada | Surrey | — |
| Islamic Academy of Saskatchewan Inc. | Prelate | $269K |
| Islamic Academy Windsor | Windsor | $526K |
| Islamic Association of Grande Prairie and District | Grande Prairie | $230K |
| Islamic Association of Medicine Hat | Medicine Hat | $45K |
| Islamic Association of Nova Scotia | Halifax | $321K |
| Islamic Association of Saskatchewan Moose Jaw Inc. | Moose Jaw | $88K |
| Islamic Association of Sault Ste. Marie | Sault Ste. Marie | $69K |
| Islamic Association of Sudbury (ias) | Sudbury | $27K |
| Islamic Association of the South Shore | Mahone Bay | $15K |
| Islamic Association of Western Canada | Surrey | $335K |
| Islamic Centre of Courtice | Bowmanville | $1.1M |
| Islamic Centre of Markham | Markham | $1.6M |
| Islamic Centre of Oshawa | Oshawa | $596K |
| Islamic Centre of Vali-E Asr | Richmond Hill | $29K |
| Islamic Charitable Services Society of Canada | Brampton | $17K |
| Islamic Circle of North America | Oakville | $29.9M |
| Islamic Community of Oakville (ICO) | Oakville | — |
| Islamic Cultural Centre of Ahlul-Beit | Windsor | $64K |
| Islamic Education & Information Centre | Don Mills | — |
| Islamic Family and Social Services Association (ifssa) | Edmonton | $3.8M |
| Islamic Foundation of Toronto | Scarborough | $4.5M |
| Islamic Heritage of Canada | Markham | $203K |
| Islamic Humanitarian Aid Canada | Hannon | $6,786 |
| Islamic Humanitarian Service | Kitchener | $5.7M |
| Islamic Humanitarian Service Foundation | Vancouver | $12K |
| Islamic Information & Da'Wah Centre International | Toronto | $891K |
| Islamic Information Foundation | Halifax | — |
| Islamic Information Society of Calgary | Calgary | $2.1M |
| Islamic Institute of Toronto | Scarborough | $3M |
| Islamic Kher Khwahi Group Inc. | Mississauga | $60K |
| Islamic Ministries of Manitoba Inc. | Oak Bluff | $81K |
| Islamic Missionary Association (Aljamiyatut Tableegh Alislamiyah) | Edmonton | $2M |
| Islamic Organization of North America Canada | Mississauga | $8,548 |
| Islamic Private Board of Education (ontario) | Brampton | $78K |
| Islamic Propagation Centre of Ontario Inc | Mississauga | $2M |
| Islamic Relief - Ir Canada | Burlington | $125.9M |
| Islamic Research Centre of Canada | Scarborough | $1.2M |
| Islamic Restoration Society - IRES | Calgary | $0 |
| Islamic School Board Ottawa | Nepean | $6,064 |
| Islamic Shia Ithna-Asheri Association of Edmonton Alberta | Edmonton | $338K |
| Islamic Shia Ithna-Asheri Association of Ottawa Canada (national Capital Region) | Nepean | $171K |
| Islamic Shia Ithna-Asheri Jamaat of Toronto | Thornhill | $11.8M |
| Islamic Social Services and Resources Association (toronto) | Toronto | $80K |