| Inspire Church | North York | $126K |
| Inspire Community Outreach Inc. | Winnipeg | $420K |
| Inspire - Community Support Services | Cornwall | $10.7M |
| Inspire Global Ministries | Airdrie | $0 |
| Inspire Ministries | Abbotsford | $135K |
| Inspire the Heart Child & Youth Society | Maple Ridge | — |
| Inspired by Wonder Inc. | Winnipeg | $2.3M |
| Inspired Children & Youth Foundation | Toronto | $302K |
| Inspired Word Apostolic Church | Sutton West | $45K |
| Inspirehealth Legacy Foundation | Vancouver | — |
| Inspirehealth Society | Vancouver | $3.2M |
| Inspiring Minds Early Learning Centre | Wellesley | $982K |
| Inspirit Foundation | Toronto | $3.4M |
| Institut Apostolique Renaissance | Sherbrooke | $4,764 |
| Institut Biblique du Québec | Longueuil | $385K |
| Institut canadien d'administration de la justice/ Canadian institute for the administration or justice | Montreal | $2.4M |
| Institut Canadien de Quebec | Quebec | $20M |
| Institut CBM | Cote Saint-Luc | $2.8M |
| Institut culturel Avataq Inc. | Westmount | $6.6M |
| Institut de Cardiologie de Montreal/montreal Heart Institute | Montreal | $335.3M |
| Institut de coopération pour l'éducation des adultes (ICÉA) | Montreal | $813K |
| Institut de Formation Humaine Intégrale de Montréal | Montreal | $1.8M |
| Institut De Formation Théologique De Montréal | Montreal | $491K |
| Institut de la liberté de conscience au Canada/Freedom of Conscience Institute in Canada | Montreal | $20K |
| Institut de la pensée juive et communautaire | Cote Saint-Luc | $108K |
| Institut de leadership des femmes de l'Ontario | Innisfil | — |
| Institut de Montréal pour la Douance et la Diversité et Montréal Institute for Giftedness and Diversity | Lachine | — |
| Institut de Notre Dame des Missions Sacred Heart College | Winnipeg | — |
| Institut de Pastorale de l'Archidiocèse de Rimouski | Rimouski | $212K |
| Institut de Recherche en Dermatologie de Montréal Montreal Dermatology Research Institute | Montreal | $568K |
| Institut de recherche en économie contemporaine | Montreal | $875K |
| Institut de Recherche Fondamentale et Clinique en Psycho-Orientation | Québec | $8,081 |
| Institut de Recherche pour le Traitement et la Prevention des Infections | Québec | — |
| Institut de Recherche Robert Sauve en Sante et en Securite du Travail | Montreal | $37.5M |
| Institut de recherche sur l'autodétermination des peuples et les indépendances nationales | Montreal | $54K |
| Institut de Recherches Cliniques de Montreal | Montreal | $47.3M |
| Institut de théologie réformée interculturel des peuples | Saint-Laurent | $13K |
| Institut d'enseignement Dar Al Iman | Ville ST-Laurent | $4.4M |
| Institut d'Enseignement de Sept-Iles Inc | Sept-Iles | $3.2M |
| Institut d'Enseignement Osteopatique du Quebec | Montreal | — |
| Institut des communications graphiques et de l'imprimabilite | Montreal | $2.9M |
| Institut des Franciscaines Missionnaires de Marie d'Ontario | Montreal | — |
| Institut des relations humaines Argyle (1985) inc./ Argyle Institute Of Human Relations (1985) Inc. | Montreal | — |
| Institut des Soeurs de Sainte-Marthe de Saint-Hyacinthe | Saint-Hyacinthe | — |
| Institut des territoires | Saint-Jerome | $915K |
| Institut Donald J. Savoie Institute | Moncton | $1.1M |
| Institut du Nouveau Monde | Montreal | $2.6M |
| Institut du patrimoine funéraire du Québec | Saint-Hyacinthe | — |
| Institut du Savoir Montfort | Ottawa | $8.9M |
| Institut économique de montréal | Montreal | $3.5M |
| Institut Fidal Inc. | Montréal | — |
| Institut Gueder Chel Torah | Saint-Laurent | $192K |
| Institut Jean-Garon | Quebec | — |
| Institut Jeanne Mance | Montreal | $82K |
| Institut Kollel Noam Eliezer | Montreal | $160K |
| Institut Marie-Guyart | Laval | — |
| Institut Missionnaire de la Consolata | Montreal | $138K |
| Institut National de la recherche scientifique | Quebec | $164.9M |
| Institut National de l'Image et du Son (inis) | Montreal | $4.9M |
| Institut national de musicothérapie National Music Therapy Institute | Mont-Royal | $173K |
| Institut national de psychiatrie légale Philippe-Pinel | Montreal | $101.5M |
| Institut Notre-Dame du Bon Conseil de Montreal | Saint-Laurent | — |
| Institut Numa/ Numa Institute | Montreal | $72K |
| Institut Pacifique/pacific Institute | Montreal-Nord | $1.9M |
| Institut Presence et Vie Inc. | Québec | — |
| Institut Québecois de la Biodiversité Inc. | Montreal | $8,648 |
| Institut québécois de réforme du droit et de la justice | Montreal | $581K |
| Institut Religieux Masculin Mère du Divin Amour (CANADA) | Saint-Leonard | — |
| Institut RocheR | Ste-Julienne | — |
| Institut Rudolf Steiner au Québec | Rosemere | $95K |
| Institut Scientifique du Saguenay Lac-ST-Jean Inc | Chicoutimi | $563K |
| Institut Secondaire Keranna (1992) Inc. | Trois-Rivieres | $8.8M |
| Institut Seculier Pie X | Quebec | $277K |
| Institut Seculier Pie X Roberval | Roberval | — |
| Institut Seculier Pie X Saguenay-Lac-St-Jean | Alma | $34K |
| Institut Seculier Pie X Section Montreal | Boucherville | $8,185 |
| Institut Seculier Pie X Section Quebec | Levis | $9,814 |
| Institut Seculier Pie X Section Saguenay | Alma | $1,743 |
| Institut Seculier Pie-X Section ST-Georges | Saint-Georges | $700 |
| Institut ST-Joseph Inc. | Quebec | $4.4M |
| Institut sur la gouvernance d'organisations privées et publiques/ The Institute for the Governance of Private and Public Organisations. | Montreal | $1.8M |
| Institut Thomas More/Thomas More Institute | Montreal | $531K |
| Institut universitaire de cardiologie et de pneumologie de Québec - Université Laval | Quebec | $404.6M |
| Institut Universitaire du Troisieme Age de Montreal | Montreal | — |
| Institut Voluntas Dei | Trois-Rivieres | $615K |
| Institut Voluntas Dei (district canadien) | Thetford Mines | $359K |
| Institut Yavne | Cote ST-Luc | $2.2M |
| Institute for a Resource-Based Economy | Toronto | $262K |
| Institute for Advanced Judaic Studies | Toronto | $4.7M |
| Institute for Advanced Talmudic and Halachic Studies | Toronto | $2.2M |
| Institute for Biblical Preaching | Cambridge | $47K |
| Institute for Bioregional Studies Limited | Charlottetown | $0 |
| Institute for Canadian Citizenship | Toronto | $6.1M |
| Institute for Catholic Education | Hamilton | $393K |
| Institute for Change Leaders | Toronto | $309K |
| Institute for Christian Action and Contemplation | Coquitlam | $239K |
| Institute for Christian Communities Montreal | Lachine | $89K |
| Institute for Christian Studies | Toronto | $845K |
| Institute for Church Partnership Evangelism | Calgary | $17K |
| Institute for Clinical Evaluative Sciences | Toronto | $35.1M |
| Institute for Consciousness Research | Markdale | $15K |
| Institute for Freedom and Justice | Moncton | $22K |
| Institute for Global Opportunities Canada ('IGo Canada') | Riverton | $86K |
| Institute for Improved Health Outcomes | Calgary | $2.6M |
| Institute for Liberal Studies Inc. | Ottawa | $410K |
| Institute for Lifelong Learning (ILL) | Toronto | $89K |
| Institute For Marketplace Transformation | Coquitlam | $126K |
| Institute for New Economics Public Interest Research Association Inc. | Victoria | $1.7M |
| Institute for Personalized Therapeutic Nutrition | Parksville | $515K |
| Institute for Positive Health for Seniors Inc /institut de Sante Positive pour Aine(e)s Inc | Orleans | $80K |
| Institute for Religion and Culture | Oliver | $46K |
| Institute For Research Education On RaceRelacions | Montreal | $113K |
| Institute for Research on Public Policy/l'institut de Recherche en Politiques Publiques | Montreal | $6.7M |
| Institute for Rural Education and Development | Calgary | $197K |
| Institute for the Advanced Study of Religion (IASR) | Toronto | — |
| Institute for the Protection of Vulnerable Persons | North York | — |
| Institute for the Study and Treatment of Pain | Vancouver | $165 |
| Institute for Understanding Sikhism | Laval | $2,275 |
| Institute of Applied Design & Technology Education Society | Richmond | $132K |
| Institute of Biblical Counselling International Society | Smithers | $79K |
| Institute of Chinese Language Culture and Arts Inc. | Winnipeg | $31K |
| Institute of Divine Metaphysical Research | Sainte-Marthe-Sur-Le-Lac | $52K |
| Institute of Gurmat Studies | Brampton | $215K |
| Institute of Italian Studies | Thunder Bay | $29K |
| Institute of Lutheran Theology Canada Society | West Kelowna | $298K |
| Institute Of Middle Eastern Education | Ancaster | $0 |
| Institute of Municipal Assessors Scholarship Trust Fund | Aurora | $15K |
| Institute of Parliamentary and Political Law (IPPL) | Ottawa | $3,054 |
| Institute of Societal Advancement In Divinity (ISAID) | Etobicoke | $735 |
| Institute of the Incarnate Word of Canada | Toronto | $261K |
| Institute of Tibetan Classics/institut des Classiques Tibetains | Montreal | $218K |
| Institution Kiuna | Wendake | $10K |
| Institution Tashbar | Montreal | $221K |
| Institution Viznitz / Viznitz Institution | Montréal | $5.7M |
| Instrumental Society of Calgary | Calgary | $37K |
| Instruments Beyond Borders Society | Vancouver | $19K |
| Instruments of Change Society | Vancouver | $15K |
| Insulin For Life Canada Association | Sherwood Park | $9,623 |
| Intact Foundation | Toronto | $4.3M |
| Intègr'action jeunesse | Quebec | $382K |
| IntégrAction La Baie | La Baie | $386K |
| IntegralOrg | Calgary | $775K |
| Integrated Health Transformation Centre Inc. | Darnley | $28K |
| Integration and Welcome Centre (IWC) | Thornhill | $724K |
| Integration Communautaire Chapleau Community Living | Chapleau | — |
| Integration Communautaire Hearst Community Living | Hearst | $1.5M |
| Intégration Compétences | Beloeil | $2M |
| Intégration jeunesse du Québec inc. | Montreal | $1.6M |
| Intégration sociale des enfants handicapés en milieu de garde (ISEHMG) | Longueuil | $339K |
| Intégration TSA | Quebec | $745K |
| Integrative Cancer Foundation of BC | Merville | — |
| Integrity Foundation | Vancouver | $0 |
| Integrity/toronto | Toronto | $2,385 |
| Integrity Worship Centre | Markham | $216K |
| Integrity's Haven Equine Rescue Centre Society (iherc) | Chester Basin | $76K |
| Intellectual Disabilities (north & West Vancouver) Society | North Vancouver | $13.7M |
| Intelligence Foundation | Montreal | $100 |
| Intengine Global Change Foundation | Vancouver | — |
| Intentional Acts of Kindness Foundation | Vancouver | $3,535 |
| Inter-A Students Society | Surrey | $89K |
| Inter-Act Theatre Society | Medicine Hat | $17K |
| Inter-action: pour l'autonomie en santé mentale de la Baie-Des-Chaleurs | New Richmond | $728K |
| Inter Arts Matrix | Kitchener | $258K |
| Inter-Cities New Life Alliance Fellowship Corporation | Warman | $235K |
| Inter-Cultural Association of Greater Victoria | Victoria | $10.1M |
| Inter-Femmes Inc. | Repentigny | $385K |
| Inter-Loge Centre-Sud | Montreal | $7.7M |
| Inter-Mennonite Chaplaincy Association Inc. | Winnipeg | $30K |
| Inter-Mountain Watershed District | Ste Rose du Lac | $1.5M |
| Inter Pares | Ottawa | $11M |
| Inter-Provincial Music Camp Foundation | Toronto | $799K |
| Inter-Val 1175 | Montreal | $1.4M |
| Inter Varsity Christian Fellowship of Canada | Etobicoke | $21.2M |
| Inter-Varsity Ministries Foundation | Toronto | — |
| Interaccess | Toronto | $604K |
| Interact Ministries of Canada | Crossfield | $2.4M |
| Interaction famille Hochelaga - Maisonneuve | Montreal | $625K |
| InterAction Loisirs | Chomedey Laval | $1.1M |
| InterAction Theatre Company Inc. | Saint John | $366K |
| Interactive Science and Technology Centre of Windsor Inc. | Windsor | — |
| Interagency Coalition on AIDS and Development- Coalition Interagence Sida et Developpement | Gloucester | — |
| Interamericana Community Self-Development Society | Vancouver | — |
| Interassociation des Personnes Handicapees du Saguenay | Chicoutimi | $244K |
| Intercede International | Fort Erie | $1.5M |
| Intercessors for Canada | Surrey | $8,989 |
| Interchurch Health Ministries Canada | Owen Sound | $5,932 |
| InterChurch Health Ministries of Saskatchewan | Saskatoon | $2,705 |
| Intercommunautaire l'Arche de Dieu/intercommunity the Ark of God | Montreal | $240K |
| Intercultural Child and Family Centre | Edmonton | $2.6M |
| Intercultural Church & Ministries | Etobicoke | $12K |
| Interdenominational Christian Community Centre Church of Camrose | Camrose | $134K |
| Interdenominational Christian Counselling Inc. | Toronto | $1.5M |
| Interfaith Committee on Chaplaincy in the Correctional Service of Canada Inc./comite Interconfessionnel de l'Aumonerie du Service Correctionnel du Canada Inc. | Mississauga | $84K |
| Interfaith Community Counselling Centre | New Hamburg | $623K |
| Interfaith Community Food Bank Society (valleyview) | Valleyview | $358K |
| Interfaith Food Bank Society of Lethbridge | Lethbridge | $5.5M |
| Interfaith Goodwill Centre | Lewisporte | $173K |
| Intergen Impact Society | Calgary | $32K |
| Intergénérations Québec | Montreal | $364K |
| Intergroupe O.a. Français de Montréal | Montreal | $65K |